Purpose: To identify a possible cause for resistance to heparin therapy.     Citations with documentation. 04.01.03 Medal Project 2002. See disclaimer.
 
data enter  
Are you evaluating a patient who appears to be resistant to heparin therapy? (Y or N) :-):-):-)  
Are the dose and route of administration adequate? (Y or N) :-):-):-)   0
Does the patient have a history of heparin-induced thrombocytopenia? (Y or N) :-):-):-)  
Does the patient have a new onset of thrombocytopenia? (Y or N) :-):-):-)  
Is the patient receiving intravenous nitroglycerin? (Y or N) :-):-):-)   0
Is the patient receiving a medication that interferes with heparin activity? (Y or N) :-):-):-)   0
Does the patient have severe acidosis? (Y or N) :-):-):-)   0
     
enter an "x" in the appropriate column for each blood level (give only 1 answer per row)  
  not tested decreased normal increased  
serum antithrombin III levels Yes 0
  not tested decreased normal increased  
serum low-density lipoproteins (LDL) Yes 0
  not tested decreased normal increased  
serum lysozyme (muramidase) Yes 0
  not tested decreased normal increased  
serum platelet factor 4 Yes 0
  not tested decreased normal increased  
serum beta-thromboglobulin Yes 0
  not tested decreased normal increased  
serum heparin cofactor II levels Yes 0
 
calculate result  
data complete? Yes  
evaluation appropriate? Yes :-):-):-)
number of possible causes identified 0  
number of potential causes not evaluated 1  
Should heparin-induced thrombocytopenia be considered? not now  
 
Workup:  
:-):-):-)  
:-):-):-)  
• Do tests not already performed.  
 

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