Purpose: To initiate and adjust heparin therapy.   Citations with documentation. 04.01.01 Sriram & Svirbely 1997
 
conversion  
body weight in pounds lbs. equals 75 kilograms
 
data enter  
body weight in kilograms kilograms  
lower end of normal PTT range in seconds seconds  
upper end of normal PTT range in seconds seconds  
 
calculate initial regimen results  
data complete? Yes  
mean of PTT normal range 29.5 seconds  
lower end therapeutic range (1.5 times mean of normal range) 44 seconds  
upper end therapeutic range (2.3 times mean of normal range) 68 seconds  
heparin bolus 6,000 units IV  
initial infusion rate (units/hour) 1,350 units per hour  
mL per hour of 50 U/mL solution (25000 U heparin in 500 mL D5W) 27 mL per hour  
perform next PTT in 6 hours  
     
 
first review enter  
measured PTT seconds  
     
evaluate results  
size of additional bolus to give NA :-):-):-)  
change in the infusion rate continue unchanged  
infusion rate in units per kilogram per hour 18 units/kg  
heparin infusion rate in units per hour 1,350 units/hour  
mls per hour of 50 U/mL 27 mL/hour  
perform next PTT in 6 hours  
     
 
second review enter  
measured PTT seconds  
     
evaluate results  
size of additional bolus to give NA :-):-):-)  
change in the infusion rate continue unchanged  
infusion rate in units per kilogram per hour 18 units/kg  
heparin infusion rate in units per hour 1,350 units/hour  
mls per hour of 50 U/mL 27 mL/hour  
perform next PTT in 6 hours  
     

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