Purpose: To initiate and adjust heparin therapy.
Citations with documentation. 04.01.01
Sriram & Svirbely 1997
conversion
body weight in pounds
lbs. equals
75
kilograms
data
enter
body weight in kilograms
kilograms
lower end of normal PTT range in seconds
seconds
upper end of normal PTT range in seconds
seconds
calculate initial regimen
results
data complete?
Yes
mean of PTT normal range
29.5
seconds
lower end therapeutic range (1.5 times mean of normal range)
44
seconds
upper end therapeutic range (2.3 times mean of normal range)
68
seconds
heparin bolus
6,000
units IV
initial infusion rate (units/hour)
1,350
units per hour
mL per hour of 50 U/mL solution (25000 U heparin in 500 mL D5W)
27
mL per hour
perform next PTT in
6 hours
first review
enter
measured PTT
seconds
evaluate
results
size of additional bolus to give
NA
:-):-):-)
change in the infusion rate
continue unchanged
infusion rate in units per kilogram per hour
18
units/kg
heparin infusion rate in units per hour
1,350
units/hour
mls per hour of 50 U/mL
27
mL/hour
perform next PTT in
6 hours
second review
enter
measured PTT
seconds
evaluate
results
size of additional bolus to give
NA
:-):-):-)
change in the infusion rate
continue unchanged
infusion rate in units per kilogram per hour
18
units/kg
heparin infusion rate in units per hour
1,350
units/hour
mls per hour of 50 U/mL
27
mL/hour
perform next PTT in
6 hours
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