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 Release 24.0, April 2009
 
The Medical Algorithms Project
Chapter : ch8. Pulmonary & Acid-Base Section : Spirometry
  Bronchodilator Response

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Copyright (c) 2006-2007, Institute for Algorithmic Medicine, Houston, TX, USA. All rights reserved.

Overview :

The response to inhaled bronchodilator is helpful in distinguishing between

(1) chronic obstructive lung disease (airway resistance relatively fixed and unresponsive to inhalation of a bronchodilator) and

(2) asthma (bronchoconstriction responds to inhalation of a bronchodilator)

 

Response to Bronchodilators

FVC (after)-to-FVC (before)

FEV1 (after)-to-FEV1 (before)

FEF(25-75%) (after)-to-FEF(25-75) (before)

not responsive

< 1.05

< 1.05

< 1.10

not clearly responsive

1.05 - 1.14

1.05 - 1.11

1.10 - 1.44

responsive

1.15 - 1.24

1.12 - 1.24

1.45 - 1.99

markedly responsive

>= 1.25

>= 1.25

>= 2.00

 

  References:

Fishman A (editor). Pulmonary Diseases and Disorders, Second Edition. McGraw-Hill Book Company. 1988. page 2508

 

 
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