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 Release 24.0, April 2009
 
Chapter : ch8. Pulmonary & Acid-Base Section : Spirometry
  FEV1-to-FVC Ratio

  Excel Sheet Reference
Copyright (c) 2006-2007, Institute for Algorithmic Medicine, Houston, TX, USA. All rights reserved.

Overview :

The FEV1-to-FVC ratio is the volume of air expired in the first second, expressed as a percent of FVC.

 

FEV1-to-FVC ratio =

= (FEV1) / (FVC ) * 100%

 

FEV1 to FVC in percent for White males 15-91 years (Crapo, 1981) =

= ((-0.13) * (height in cm)) - (0.152 * (age in years)) + 110.49

 

FEV1 to FVC in percent for White females 15-84 years (Crapo, 1981) =

= ((-0.202) * (height in cm)) - (0.252 * (age in years)) + 126.58

 

FEV1 to FVC in percent for Hispanic males 25-75 years (Crapo, 1990) =

=(-0.1160 * (age in years)) + 86.5881

 

FEV1 to FVC in percent for Hispanic females 20-80 years (Crapo, 1990) =

=(-0.1862 * (age in years)) + 91.7259

 

FEV1 to FVC in percent for White males 65-85 years (Enright, 1993) =

= (-0.294 * (age in years)) + 93.8

 

FEV1 to FVC in percent for White females 65-85 years (Enright, 1993) =

= (-0.242 * (age in years)) + 92.3

 

FEV1 to FVC in percent for White males 18-86 years years (Roberts, 1991) =

= (-21.476 * (height in meters)) - (0.242* (age in years)) + 126.252

 

FEV1 to FVC in percent for White females 18-86 years (Roberts, 1991) =

= (-0.172 * (age in years)) + 88.134

 

Interpretation:

• The FEV1/FVC ratio reflects the severity of pulmonary impairment in obstruction.

 

FEV1 to FVC ratio

Interpretation

>= 70% of predicted

normal

61 - 69% of predicted

mild obstruction

45 - 60% of predicted

moderate obstruction

< 45% of predicted

severe obstruction

 

  References:

Crapo RO, Morris AH, Gardner RM. Reference spirometric values using techniques and equipment that meet ATS recommendations. Am Rev Respir Dis 1981; 123:659-664.

Crapo RO, Jensen RL, et al. Normal spirometric values in healthy Hispanic Americans. Chest. 1990; 98: 1435-1439.

Enright PL, Krnmal RA, et al. Spirometry reference ranges for women and men 65 to 85 years of age. Cardiovascular Health Study. Am Rev Respir Dis. 1993; 147: 125-133.

Fishman A (editor). Pulmonary Diseases and Disorders, Second Edition. McGraw-Hill Book Company. 1988. page 2507.

Roberts CM, MacRae KD, et al. Reference values and prediction equations for normal lung function in a non-smoking white urban population. Thorax. 1991; 46: 643-650.

Wanger J. Pulmonary Function Testing. A Practical Approach. Second Edition. Williams & Wilkins. 1996. Table A4.3, page 275.

 

 

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