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Overview :
Following injection of a dye into
the bloodstream, its concentration rises briefly, then falls exponentially
until recirculation occurs, whereupon it rises again slightly. Measurement of
the dye directly or indirectly correlates with the cardiac output.
Parameters:
(1) indicator dose in mg
(2) mean blood concentration of
indicator in mg/L
(3) duration of curve in seconds
cardiac output in liters per
minute =
= ((amount of indicator injected
in mg) * 60) / ((mean concentration of indicator in the blood in mg/L) * (time
of total curve duration in seconds))
where:
• 60 represents the number of
seconds per minute
• The area under the curve can
help determine the mean concentration of the indicator.
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