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 Release 24.0, April 2009
 
Chapter : ch15. Obstetics & Gynecology Section : Maternal Assessment During Pregnancy
  Criteria for the Diagnosis of Pre-Eclampsia and Eclampsia

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Copyright (c) 2006-2007, Institute for Algorithmic Medicine, Houston, TX, USA. All rights reserved.

Overview :

Hypertension occurring during pregnancy needs to classified correctly in order to guide medical therapy.

 

Chronic hypertension is defined as a blood pressure > 140/90 mm Hg in

(1) a nonpregnant female

(2) before 20 weeks of gestation

(3) persisting more than 6 weeks post-partum

 

Late or transient hypertension:

(1) development of hypertension during pregnancy without other signs of pre-eclampsia

 

Pre-eclampsia:

(1) onset of hypertension at greater than 20 weeks of gestation with proteinuria and/or edema

(2) hypertension: blood pressure greater than 140/90 mm Hg on more than 2 occasions greater than 6 hours apart

(3) proteinuria: greater than 300 mg per 24 hours or urine dipstick greater than 1+ on 2 occasions more than 6 hours apart

(4) hyperuricemia greater than 5 mg/dL

 

Chronic hypertension with superimposed pre-eclampsia:

(1) exacerbation of chronic hypertension greater than 30 mm Hg systolic or 15 mm Hg diastolic, plus the appearance of significant proteinuria

 

Severe pre-eclampsia - when one or more of the following is present:

(1) blood pressure greater than 160 mm Hg systolic or 110 mm Hg diastolic on 2 occasions more than 6 hours apart

(2) proteinuria greater than 5 grams per 24 hours or 3-4+ by dipstick

(3) oliguria less than 400 mL per 24 hours

(4) cerebral or visual disturbances

(5) pulmonary edema or cyanosis

 

Eclampsia is defined as the presence of seizures in a patient with preeclampsia.

 

  References:

Egerman RS, Witlin AG, et al. Thrombotic thrombocytopenic purpura and hemolytic uremic syndrome in pregnancy: Review of 11 cases. Am J Obstet Gynecol. 1996; 175: 950-956.

Silver H. Chapter 18: Hypertensive disorders. pages 283-295 (page 283). IN: Niswander KR, Evans AT (editors). Manual of Obstetrics, Fifth Edition. Little, Brown and Company. 1996.

 

 

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