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 Release 21.0, Jan 2008
 
Chapter : ch8. Pulmonary & Acid-Base Section : Spirometry
  Equations of Ong et for Predicting FEV1, PEFR and FVC in Malnourished Indian Pediatric Patients

  Excel Sheet Reference
Copyright (c) 2006-2007, Institute for Algorithmic Medicine, Houston, TX, USA. All rights reserved.

Overview :

Ong et al evaluated pulmonary function tests in malnourished children from West Bengal, India. They identified equations that can be used to estimate target values based on sitting height and weight. The authors are from the University of Dundee.

 

Patient selection: malnourished children from 3 to 17 years (page 18)

 

Parameters:

(1) sitting height in cm

(2) body weight in kilograms

 

Predicted pulmonary function tests:

(1) FEV1 (forced expiratory volume in 1 second) in liters

(2) FVC (forced vital capacity) in liters

(3) PEFR (peak expiratory flow rate) in liters per second

 

observed pulmonary function test as percent of predicted =

= (observed value) / (predicted) * 100%

 

For Boys

 

predicted FEV1 in liters =

= EXP(X)

 

X =

= (1.080 * (LN(sitting height))) + (0.657 * (LN(weight))) - 6.261

 

predicted FVC in liters =

= EXP(Y)

 

Y =

= (LN(sitting height)) + (0.669 * (LN(weight))) - 5.918

 

predicted PEFR in liters per second =

= EXP(Z)

 

Z =

= (0.781 * (LN(sitting height))) + (0.614 * (LN(weight))) + 0.378

 

For Girls

 

predicted FEV1 in liters =

= EXP(X)

 

X =

= (1.268 * (LN(sitting height))) + (0.518 * (LN(weight))) - 6.667

 

predicted FVC in liters =

= EXP(Y)

 

Y =

= (1.233 * (LN(sitting height))) + (0.527 * (LN(weight))) - 6.529

 

predicted PEFR in liters per second =

= EXP(Z)

 

Z =

= (1.545 * (LN(sitting height))) + (0.338 * (LN(weight))) - 2.093

 

NOTE: While working on the spreadsheet it became apparent that the predicted PEFR by these equations are significantly higher than expected and what seems reasonable. Using -7.093 for girls gives a more reasonable value, suggesting a typographical error. Alternatively the PEFR value does not need to be made EXP.

 

  References:

Ong TJ, Mehta A, et al. Prediction of lung function in the inadequately nourished. Arch Dis Child. 1998; 79: 18-21 (Table 4, page 20).

 

 

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