Overview :

The Forced Expiratory Volume in 1 second (FEV1) can be predicted in pediatric patients based on height and other physical characteristics.

NOTE: Quanjer et al provides many additional equations for FEV1.

Linear Equations Based on Height

FEV1 in liters for males 5-18 years old and 42-59 inches tall (Dickman) =

= (0.085 * (height in inches)) - 2.855

FEV1 in liters for males 5-18 years old and 60-78 inches tall (Dickman) =

= (0.121 * (age in years)) + (0.143 * (height in inches)) - 7.864

FEV1 in liters for females 5-18 years old and 42-59 inches tall (Dickman) =

= (0.074 * (height in inches)) - 2.482

FEV1 in liters for females 5-18 years old and 60-78 inches tall (Dickman) =

= (0.085 * (age in years)) + (0.10 * (height in inches)) - 4.939

FEV1 in liters for 4 to 18 years (Weng and Levinson) =

= (0.040 * (height in cm)) - 3.99

FEV1 in liters for boys 5 to 18 years (Godfrey) =

= (0.051 * (height in cm)) - 4.77

FEV1 in liters for girls 5 to 18 years (Godfrey) =

= (0.041 * (height in cm)) - 3.35

FEV1 in liters for boys 4-19 years < 162.6 cm (Rosenthal) =

= (0.034 * (height in cm)) - 2.780

FEV1 in liters for boys 4-19 years >= 162.6 cm (Rosenthal) =

= (0.052 * (height in cm)) - 5.108

FEV1 in liters for girls 4-19 years < 152.6 cm (Rosenthal) =

= (0.033 * (height in cm)) -2.734

FEV1 in liters  for girls 4-19 years >= 152.6 cm (Rosenthal) =

= (0.041 * (height in cm)) - 3.680

Exponent of Height

FEV1 in liters for 7 to 19 year olds (Hsu et al) =

= A * 10^(-3) * ((height in cm)^B)

FEV1 in liters (Polgar and Promadhat) =

= (0.0000021 * ((height in cm)^2.8))

FEV1 in liters for 5 to 25 years of age (Lebowitz et al) =

= 6.844 + (0.040 * (age in years)) - (0.281 * (height in inches)) + (0.003 * ((height in inches)^2))

Natural Logarithm

FVC in liters (Wang et al) =

= EXP((B * (LN(height in meters))) + A)

Cotes JE. Lung Function. Assessment and Application in Medicine. Fifth Edition. Blackwell Scientific Publications. 1993. pages 460 and 465.

Dickman ML, Schmidt CD, Gardner RM. Spirometric standards for normal children and adolescents (ages 5 years thorugh 18 years). Am Rev Resp Dis. 1971; 104: 680-687. (Table 3, page 684).

Godfrey S, Kamburoff PL, et al. Spirometry. Lung volumes and airway resistance in normal children aged 5 to 18 years. Br J Dis Chest. 1970; 64: 15-24.

Hsu KHK, Jenkins DE, et al. Ventilatory functions of normal children and young adults - Mexican-American, white and black. I. Spirometry. Journal of Pediatrics. 1979; 95: 14-23.

Lebowitz MD, Holberg CJ, et al. Longitudinal study of pulmonary function development in childhood, adolescence, and early adulthood. Am Rev Respir Dis. 1987; 136: 69-75.

Polgar G, Promadhat V. Pulmonary function testing in children. WB Saunders. 1971. page 211.

Quanjer PH, Stocks J, et al. Compilation of reference values for lung function measurements in children. Eur Respir J. 1989; 2 (Supplement 4): 184s - 261s.

Rosenthal M, Cramer D, et al. Lung function in white children aged 4 to 19 years. II. Single breath analysis and plethysmography. Thorax. 1993; 48: 803-808.

Wang X, Dockery DW, et al. Pulmonary function between 6 and 18 years of age. Pediatric Pulmonology. 1993; 15: 75-88.

Wanger J. Pulmonary Function Testing. A Practical Approach. Second Edition.  Williams & Wilkins. 1996. Table A6.2, page 284.

Weng TR, Levison H. Standards of pulmonary function in children. Am Review Resp Disease. 1969; 99: 879-894.