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 Release 21.0, Jan 2008
 
Chapter : ch5. Transfusion Medicine Section : Estimation of Blood Loss and Prediction of Blood Transfusion Needs
  Risk Factors of Kinnaird et al for Major Blood Loss and for Transfusion Following a Percutaneous Coronary Intervention (PCI)

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Overview :

Kinnaird et al identified risk factors for major blood loss and for blood transfusion following a percutaneous coronary intervention (PCI). These can help identify patients who may benefit from more aggressive management. The authors are from Washington Hospital Center (Washington, D.C.), Cardiovascular Research Foundation (NYC) and Rabin Medical Center (Israel).

 

The TIMI criteria were used to define major and minor bleeding (see Section 06.09.14).

 

Risk factors for major bleeding:

(1) age > 80 years

(2) use of an intra-aortic balloon pump (IABP)

(3) hypotension during the procedure

 

The presence a major bleed associated with PCI was associated with an increased risk for  in-hospital and 1 year mortality. The occurrence of a stroke had the highest odds ratio for in-hospital and 1 year mortality.

 

Risk factors for receiving a blood transfusion:

(1) retroperitoneal bleeding

(2) gastrointestinal bleeding (with gross hematemesis, heme-positive coffee ground emesis, or heme-positive melena)

(3) large hematoma (palpable swlelling >= 4 cm in diameter) at arterial access site

(4) age > 80 years

 

where:

• The first 3 items for predicting blood transfusion are the criteria for clinical bleeding.

 

  References:

Kinnaird TD, Stabile E, et al. Incidence, predictors, and prognostic implications of bleeding and blood transfusion following percutaneous coronary interventions. Am J Cardiol. 2003; 92: 930-935.

 

 

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