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 Release 22.0, Sept. 2008
 
Chapter : ch5. Transfusion Medicine Section : Estimation of Blood Loss and Prediction of Blood Transfusion Needs
  Adjusted Blood Requirement Index (ABRI) in a Patient with Portal Hypertension and Upper Gastrointestinal Bleeding

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Overview :

The Adjusted Blood Requirement Index (ABRI) can be used to evaluate a patient with upper gastrointestinal bleeding in the setting of portal hypertension.

 

Parameters:

(1) initial hematocrit in percent (as a whole number from 0 to 100)

(2) final hematocrit in percent (as a whole number from 0 to 100)

(3) number of units of blood transfused

 

ABRI =

= (number of units of packed RBCs transfused) / ((final hematocrit) - (initial hematocrit) + 0.01)

 

where:

• The 0.01 is allows for the initial and final hematocrits are the same.

• The hemoglobin and hematocrit should be monitored every 6 hours for the first 2 days then every 12 hours until the bleeding is under control.

• The target hematocrit for a patient without cardiopulmonary disease who has had active GI bleeding is 24 percent (a hemoglobin of 8 g/dL).

 

Interpretation:

• minimum ABRI: a negative number

• maximum ABRI: > 100

• The typical ABRI for transfusion after bleeding is controlled is around 0.33. (A single unit of packed RBCs will raise the hemoglobin 1 g/dL in the absence of blood loss.)

• An ABRI >= 0.75 indicates that active bleeding is still occurring.

 

NOTE: A negative number (when initial hematocrit > final hematocrit) probably also indicates a failure to control hemorrhage.

 

  References:

De Franchis R. Evolving consensus in portal hypertension. Report of the Baveno IV Consensus Workshop on methodology of diagnosis and therapy in portal hypertension. J Hepatology. 2005; 43: 167-176.

 

 

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