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 Release 22.0, Sept. 2008
 
Chapter : ch5. Transfusion Medicine Section : Estimation of Blood Loss and Prediction of Blood Transfusion Needs
  Determining the Percent Red Blood Cell Volume Replaced Based on the Patient's Body Weight

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Copyright (c) 2008-2010, Institute for Algorithmic Medicine, Houston, TX, USA. All rights reserved.

Overview :

The volume of red blood cell transfused may be expressed in mL per kg, especially in children. This can be used to estimate the percent red blood cell volume replaced.

 

Parameters:

(1) total volume of packed red blood cells transfused

(2) hematocrit of packed red blood cells (usually 70-80%)

(3) age and gender of patient

(4) lean body weight

 

Red blood cell volume based on lean body weight (LBW) tends to be more accurate than that based on actual body weight.

 

red cell volume transfused in mL =

= (total volume transfused in mL) * (hematocrit as a percent) / 100

 

percent of red cell volume transfused =

= (red cell volume transfused in mL) / (estimated red blood cell volume in mL) * 100%

 

 

Red Blood Cell Volume in mL/kg LBW

Age of the Patient

Male

Female

premature

50

50

0-1 days

39

39

2-30 days

36

36

1-2 months

26

26

3-6 months

23

23

7-12 months

25

25

1-10 years

28

27

>= 11

28

25

from data in Chapter 02 (Section 02.10)

 

  References:

Jacobs DS, Demott WR, et al. Laboratory Test Handbook, 4th Edition. Lexi-Comp Inc. 1996.  page 345.

Linderkamp O, Versmold HT, et al. Estimation and prediction of blood volume in infants and children. Europ J Pediat. 1977; 125: 227-234.

Technical Manual of the American Association of Blood Banks, 12th edition. American Association of Blood Banks. 1996. Appendix 3, page 730.

Technical Manual Committee. Technical Manual, 14th Edition. AABB. 2002. pages 738-739.

 

 

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