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 Release 22.0, Sept. 2008
 
Chapter : ch43. Medical Genetics Section : Guidelines and Indications for Genetic and Chromosome Analysis
  Ethical Guidelines of Ross and Moon for Genetic Testing of a Child

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Overview :

Ross and Moon offered ethical guidelines for genetic testing. Genetic testing of children is one of the most sensitive areas.

 

Considerations:

(1) symptomatic child

(2) child from a high risk family

(3) genetic disease that is a threat to public health

(4) genetic disease in which early diagnosis can significantly reduce morbidity and/or mortality

 

Genetic testing is indicated if:

(1) The child is symptomatic and a genetic condition is suspected.

(2) The child is from a high risk family and early diagnosis can reduce morbidity and/or mortality.

(3) There is a condition which has sufficient public health impact to justify universal screening.

 

Genetic testing is not indicated if:

(1) The child is symptomatic but a genetic condition is not suspected.

(2) The child is not from a high risk family, there are no public health reasons for testing and early diagnosis does not decrease morbidity and/or mortality.

 

Genetic testing is controversial if:

(1) The child is from a high risk family and early diagnosis does not impact morbidity and/or mortality.

(2) The child is not from a high risk family, there are no public health reasons for testing and early diagnosis may decrease morbidity and/or mortality. This may be justifiable in targeted persons with specific risk factors.

 

  References:

Ross LF, Moon MR. Ethical issues in genetic testing of children. Arch Pediatrics Adolescent Medicine. 2000: 154: 873-879. (Figure 1, page 876; Figure 2, page 877).

 

 

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