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Overview :
The effective half-life for a radionuclide within the body
is the period of time needed for the compound to be decreased by 50%. This
occurs due to the combined effect of the biological half-life and the physical
half-life for the compound.
Definitions:
• The
biological half-life is the time required for half of the material to be
eliminated from body through excretion in urine, stool, sweat or other routes.
• The physical
half-life is the time required for the compound to loss half of its activity
through radioactive decay.
effective half-life =
= ((biological half-life) * (physical half-life)) /
((biological half-life) + (physical half-life))
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