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 Release 22.0, Sept. 2008
 
The Medical Algorithms Project
Chapter : ch24. Parasitology & Medical Entomology Section : Malaria
  Malaria Prognosis Score (MPS) of Mishra et al for Predicting Mortality in an Adult with Severe Falciparum Malaria

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Copyright (c) 2008-2010, Institute for Algorithmic Medicine, Houston, TX, USA. All rights reserved.

Overview :

Mishra et al developed the Malaria Prognosis Score (MPS) for predicting mortality in an adult with severe falciparum malaria. This can help identify a patient who may benefit from more aggressive management. The authors are from Ispat General Hospital (India), Sushilavati Government Women's College (India) and the University of Maryland in Baltimore.

 

Patient selection: adult with falciparum malaria

 

Parameters:

(1) severe anemia

(2) acute renal failure

(3) acute respiratory distress (ARDS)

(4) cerebral malaria (with unrousable coma)

 

Parameter

Finding

Points

severe anemia

absent (hemoglobin >= 5 g/dL)

0

 

present (hemoglobin < 5 g/dL)

1

acute renal failure

absent

0

 

present (serum creatinine > 3 mg/dL)

2

respiratory distress with need for mechanical ventilation

absent

0

 

present

3

cerebral malaria

absent

0

 

present (unrousable coma)

4

 

malaria prognosis score =

= SUM(points for all 4 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 10

• The higher the score the greater the risk of mortality.

 

MPS

Risk Group

Mortality Rate

0, 1 or 2

low

2%

3 or 4

low to moderate

10%

5 or 6

moderate

40%

7 to 10

high

90%

 

  References:

Mishra SK, Panigrahi P, et al. Prediction of outcome in adults with severe falciparum malaria: a new scoring system. Malaria Journal. 2007; 6: 24. doi: 10.1186/1475-2875-6-24.

 

 
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