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 Release 21.0, Jan 2008
 
Chapter : ch24. Parasitology & Medical Entomology Section : Malaria
  Algorithm of Beare et al for Evaluating a Comatose Child with Malaria and Malarial Retinopathy

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Overview :

Beare et al developed an algorithm for the use of malarial retinopathy in the evaluation of a comatose child with malaria. In an area endemic for malaria coma may be due to a cause other than the malaria. The authors are from Blantyre (Malawi), Royal Liverpool University, Michigan State University, and Tumaini University in Moshi, Tanzania.

 

Patient selection: comatose child with malarial parasitemia

 

The child's fundus is examined for findings of malarial retinopathy:

(1) papilledema

(2) retinal whitening

(3) vascular changes

(4) retinal hemorrhages

(5) cotton wool spots

 

If malarial retinopathy is diagnosed, then it is graded as mild, moderate or severe.

 

Results of Fundus Exam

Interpretation

normal

evaluate for other causes of coma; treat for malaria

papilledema only (without other changes)

evaluate for other causes of raised intracranial pressure; treat for malaria

malarial retinopathy

confirms diagnosis of cerebral malaria; treat for malaria

 

Poor prognostic findings - one or both of the following

(1) severe malarial retinopathy

(2) malarial retinopathy with papilledema

 

The number of retinal hemorrhages correlates with the number of cerebral hemorrhages.

 

  References:

Beare NAV, Taylor TE, et al. Malarial retinopathy: A newly established diagnostic sign in severe malaria. Am J Trop Med Hygiene. 2006; 75: 790-797. (Figure 7, page 794)

 

 

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