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 Release 21.0, Jan 2008
 
Chapter : ch24. Parasitology & Medical Entomology Section : Malaria
  Management of a Patient with Malaria and Spontaneous Rupture of the Spleen

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Copyright (c) 2006-2007, Institute for Algorithmic Medicine, Houston, TX, USA. All rights reserved.

Overview :

A patient with malaria and splenomegaly may have rupture of the spleen. This can be managed conservatively in many cases provided certain criteria are met. The management is similar to that for traumatic rupture of the spleen.

 

Criteria for conservative management:

(1) hemodynamically stable (normotensive with stable pulse)

(2) no signs of clinical deterioration (clinically stable)

(3) stable hemoglobin with <= 2 units of blood transfused

(4) compliant with bed rest

 

where:

• The time period over which the blood is transfused is not stated.

• According to Hamel et al, spontaneous rupture of the spleen is more of a problem for Plasmodium vivax infections.

 

Features of conservative management:

(1) scrupulous bed rest for several weeks, until completely resolved

(2) careful monitoring

(3) periodic CT scans to monitor resolution of injury or to detect expansion

(4) access to emergency services if signfiicant rupture occurs

 

Delayed rupture may occur with medical management, especially if the conservative management is stopped too soon.

 

If surgery is required, then surgical repair or partial resection should be tried, with complete splenectomy performed only when all else fails.

 

  References:

Hamel CT, Blum J, et al. Nonoperative treatment of splenic rupture in malaria tropica: review of literature and case report. Acta Trop. 2002; 82: 1-5.

Imbert P, Rapp C, Debord T. Spontaneous rupture of the spleen during malaria: A conservative treatment is appropriate for selected cases (Letter to the Editor). Clin Infect Dis (CID). 2006; 42: 1207-1208.

Jacobs FM, Prat D, et al. Spontaneous rupture of the spleen during malaria: A conservative treatment is appropriate for selected cases (Letter to the Editor). Clin Infect Dis (CID). 2005; 40: 1858-1859.

Rapp C, Debord T, et al. Splenic rupture in infectious disease: splenectomy or conservative treatment? Report of three cases. Rev Med Interne. 2002; 23: 85-91.

 

 

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