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 Release 21.0, Jan 2008
 
Chapter : ch24. Parasitology & Medical Entomology Section : Malaria
  Recommendations of Maitland et al for Glucose and Electrolyte Correction in a Pediatric Patient with Severe Malaria

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Overview :

Maitland et al listed measures for correcting abnormal glucose and elelctrolyte concentrations in pediatric patients with severe malaria. The authors are from the Kenya Medical Research Institute, Wellcome Trust, St. Mary's Hospital (London), University of Oxford and University of Sussex.

 

Parameters measured:

(1) glucose

(2) potassium

(3) total calcium

(4) magnesium

(5) phosphate

 

Parameter

Correct If

glucose

< 3.0 mmol/L (54 mg/dL)

potassium

< 3.5 mmol/L (3.5 mEq/L)

total calcium

< 2.0 mmol/L (8.0 mg/dL)

magnesium

< 0.75 mmol/L (1.82 mg/dL)

phosphate

< 0.7 mmol/L (2.17 mg/dL)

 

 

Parameter

Parenteral Correction Protocol

glucose

10% dextrose, 5 mL * (body wgt in kg)

potassium

(0.25 mmol * (body wgt in kg)) over 30 minutes

total calcium

10% calcium gluconate, (0.3 mL * (body wgt in kg)) over 30 minutes

magnesium

50% magnesium sulfate, (0.2 mL * (body wgt in kg)) over 30 minutes

phosphate

sodium phosphate, (0.2 mmol * (body wgt in kg)) over 30 minutes

 

  References:

Maitland K, Nadel S, et al. Management of severe malaria in children: proposed guidelines for the United Kingdom. BMJ. 2005; 331: 337-343 (Table 2, page 341).

 

 

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