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Overview :
Gerardin et al identified risk factors for mortality in African
children with falciparum malaria. This can help identify patients who may
benefit from more aggressive management and closer monitoring. The authors are
from Dakar in Senegal and Lille, Marseille and Saint-Mande in France.
Location: Dakar, Senegal
Parameters:
(1) platelet count
(2) cerebral malaria
(3) respiratory distress
(4) blood glucose
(5) organ failure
|
Risk
Factor |
Odds Ratio |
|
thrombocytopenia
with platelet count < 100,000 per µL |
13 |
|
cerebral
malaria |
30 |
|
respiratory distress |
4 |
|
hypoglycemia with glucose < 2.2 mmol/L |
6 |
|
one or more organ failures (below) |
29 |
Organ failures:
(1) renal
failure with elevated serum creatinine
(2) collapse
(systolic hypotension with blood pressure < 60 mm Hg if <= 5 years of age
or < 80 mm Hg if > 5 years of age)
(3) abnormal
bleeding (coagulopathy)
(4) pulmonary
edema
For the implementation I used a simple score, with respiratory
distress and hypoglycemia as 1 point; thrombocytopenia 2 points; cerebral
malaria and organ failures 4 points.
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