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 Release 21.0, Jan 2008
 
Chapter : ch24. Parasitology & Medical Entomology Section : Malaria
  Algorithm of Stauffer and Fischer for Evaluation of a Patient Clinically Suspected of Having Malaria

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Overview :

Stauffer and Fischer developed a flow diagram for evaluating a patient suspected of having malaria. This can help guide initial diagnostic testing and management. The authors are from the University of Minnesota and Mayo Clinic.

 

Patient selection: malaria suspected based on history of exposure together with signs and symptoms of malaria

 

Parameters:

(1) Does the patient appear toxic?

(2) Is Plasmodium falciparum the dominant species in the exposure area?

(3) Is the patient likely to be partially immune to falciparum malaria?

 

Criteria for partial immunity to falciparum malaria - all of the following:

(1) > 6 years of age

(2) history of malaria infection

(3) resided in an area where malaria is highly endemic within past 2 years

 

If toxic:

(1) admit to hospital ICU

(2) perform multiple thick and thin smears

(3) consider PCR if available

(4) start parenteral therapy

 

If non-falciparum species suspected:

(1) perform thick and thin smears

(2) if initial smears are negative repeat as outpatient every 8-12 hours for minimum of 3 sets

 

If Plasmodium falciparum suspected and the patient likely has partial immunity:

(1) perform thick and thin smears

(2) if initial smears are negative repeat as outpatient every 8-12 hours for minimum of 3 sets

 

If Plasmodium falciparum suspected and the patient is likely nonummune:

(1) admit to the hospital

(1) perform thick and thin smears

(2) if initial smears are negative repeat every 8-12 hours and with fevers

 

  References:

Stauffer W, Fischer PR. Diagnosis and treatment of malaria in children. Clin Infect Dis. 2003; 37: 1340-1348 (Figure 1, page 1343).

 

 

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