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 Release 21.0, Jan 2008
 
Chapter : ch24. Parasitology & Medical Entomology Section : Malaria
  Risk Factors Associated with Death from Malaria for a Traveler from a Developed Country

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Overview :

Kain identified a series of risk factors seen in travelers from developed countries who died from malaria. These factors can help direct efforts to reduce unnecessary mortality.

 

Preventable risk factors in travelers who died from malaria:

(1) failure to take appropriate chemoprophylaxis

(2) failure of the physician to consider malaria as a diagnosis when the patient initially presented

(3) failure of the laboratory to detect or properly identify the parasite

(4) treatment with an inappropriate drug regimen

(5) drug regimen administered by an inappropriate route (oral when intravenous route indicated)

 

Based on these factors, the following steps can reduce mortality:

(1) A traveler to a malarial region should use appropriate chemoprophylaxis.

(2) A physician should always consider malaria in a patient how gives an appropriate travel history.

(3) Laboratories should be familiar and proficient in the identification of malaria.

(4) Treatment should consist of appropriate drugs delivered by an effective route, based on recommendations from the CDC, an infectious disease consultant or other health resource.

 

  References:

Centers for Disease Control and Prevention (CDC). Malaria deaths following inappropriate malaria chemoprophylaxis - United States. MMWR. 2001; 50: 597-599.

Kain KC, Macpherson DW, et al. Malaria deaths in visitors to Canada and in Canadian travelers: a case series. Can Med Assoc J. 2001; 164: 654-659.

Kain KC. Atovaquone/Proguanil: The need for family protection. J Travel Med. 2003; 10 (Supplement 1): S8-S12 (page S8).

 

 

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