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 Release 22.0, Sept. 2008
 
Chapter : ch23. Microbiology & Infectious Diseases Section : Evaluation of Bacteremias and Sepsis
  Risk Factors of Mylotte and Tayara for 30-Day Mortality in a Patient with Staphylococcus aureus Bacteremia

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Overview :

Mylotte and Tayara identified risk factors associated with short term (30-day) mortality in patients with Staphylococcus aureus bacteremia. These can help identify patients who may benefit from closer monitoring and more aggressive management. The authors are from the University of Buffalo, State University of New York, and Erie County Medical Center.

 

Patient selection: adults with Staphylococcus aureus bacteremia (excluding obstetrical patients)

 

Parameters:

(1) age of the patient in years

(2) source for the bacteremia

(3) diabetes mellitus

(4) acute physiology score (APS) from the APACHE III score

 

Parameter

Finding

Points

age of the patient in years

< 65 years of age

0

 

>= 65 years of age

2

source

respiratory (pneumonia, etc.)

6

 

unknown

4

 

other

0

diabetes mellitus

absent

0

 

present

2

APS

<= 60

0

 

> 60

16

 

where:

• Sources of bacteremia included: IV catheter, osteomyelitis, skin or soft tissue, intra-abdominal, and urinary tract.

• The points assigned are based on the odds ratios from Table 4, page 1173, rounded to nearest integer.

• The APS is discussed in Chapter 30. The range is 0 to 192.

 

NOTE: The following score was not included in the article and has not been validated.

 

total score =

= SUM(points for all 4 risk factors)

 

Interpretation:

• minimum score: 0

• maximum score: 30

• The higher the score the greater the risk for 30-day mortality.

 

  References:

Mylotte JM, Tayara A. Staphylococcus aureus bacteremia: Predictors of 30-day mortality in a large cohort. Clinical Infectious Diseases. 2000; 31: 1170-1174.

 

 

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