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 Release 21.0, Jan 2008
 
Chapter : ch16. Male Genital System Section : Semen Analysis
  Adequacy of Semen Specimen for Analysis

  Excel Sheet Reference
Copyright (c) 2006-2007, Institute for Algorithmic Medicine, Houston, TX, USA. All rights reserved.

Overview :

For valid conclusions to be made from semen analysis, it is important that a good specimen be collected and properly delivered.

 

Some test results affected by poor specimen collection:

(1) gross appearance

(2) volume (low)

(3) motility (poor)

(4) viability (poor)

(5) viscocity (high or low)

(6) density (low)

(7) morphology (degenerate forms)

 

Parameters for Good Sperm Sample

 

Period of abstinence before specimen collection:

• ideally 3-4 days

• if < 2 days: the sperm density may be low

• if > 4 days: the sperm may show a reduced motility and viability

 

Manner of collection:

• Masturbation most practical.

• Coitus interruptus may result in loss of the first portion of the ejaculate.

 

Sample collection:

• The entire specimen should be collected. Sometimes a "split" sample is collected, with the first and subsequent portions kept separate.

• The loss of the first portion of the ejaculate: associated with reduced sperm count since first portion has the highest concentration of spermatozoa.

• Samples recovered from vagina may have incomplete volume recovery and be diluted by vaginal secretions.

 

Collection container:

• Clean, dry wide-mouthed glass or hard plastic container provided by the laboratory should be used.

• Glass jars or containers from the home may contain detergents or other contaminants

• Soft plastic containers are associated with reduced viability and motility for spermatozoa

• Regular condoms may result in incomplete volume recovery and may contain spermicides.

• Special condoms for sperm collection may result in incomplete volume recovery.

 

Time for delivery after collection:

• 1 hour or less optimum

• Longer periods result in specimen deterioration with reduced motility.

 

Temperature during transportation:

• The container should be warmed to body temperature before specimen collection.

• The specimen should be maintained at body temperature until delivered to the laboratory.

• The specimen should be protected from temperature extremes.

 

  References:

Adelman MM, Cahill EM. Atlas of Sperm Morphology. ASCP Press. 1989. Chapter 1: Routine semen analysis. pages 2-13

Sarkar S, Henry JB. Chapter 22: Andrology laboratory and fertility assessment. pages 507-514. IN: Henry JB. Clinical Diagnosis and Management by Laboratory Methods, Nineteenth Edition. WB Saunders Company. 1996.

 

 

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