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 Release 21.0, Jan 2008
 
Chapter : ch12. Nutrition Section : Vitamin Assessment
  Vitamin A Therapy in a Child with Measles

  Excel Sheet Reference
Copyright (c) 2006-2007, Institute for Algorithmic Medicine, Houston, TX, USA. All rights reserved.

Overview :

A young child with measles and low reserves of vitamin A may develop clinical vitamin A deficiency and/or severe measles complications. Replacement doses of vitamin A are recommeded for these patients.

 

Patient selection: measles and increased risk for depressed vitamin A stores

 

Exclusion: child with evidence of hypervitaminosis A

 

Risk for reduced vitamin A stores in a pediatric patient:

(1) child < 5 years in a developing country

(2) child < 2 years in a developed country AND hospitalized

(3) fat malabsorption

 

Prophylaxis: 1 dose daily for 2 days

 

Age of Patient

Oral Dose of Vitamin A

< 12 months

100,000 IU

>= 12 months

200,000 IU

 

where:

• 1 IU vitamin A = 0.3 µg retinol equivalent (RE)

 

If the patient has malabsorption or diarrhea then vitamin A can be given parenterally, but the dose may be lower (check with a nutritionist).

 

NOTE: An older patient with measles and malnutrition, malabsorption or vitamin A deficiency may also benefit from prophylactic therapy with vitamin A.

 

  References:

Perry RT, Halsey NA. The clinical significance of measles: A review. J Infect Dis (JID). 2004; 189 (Supplement 1): S4 - S16.

 

 

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