Not Logged In     Login  
 Release 21.0, Jan 2008
 
Chapter : ch12. Nutrition Section : Vitamin Assessment
  Clinical Features of Scurvy (Vitamin C Deficiency)

  Excel Sheet Reference
Copyright (c) 2006-2007, Institute for Algorithmic Medicine, Houston, TX, USA. All rights reserved.

Overview :

Scurvy is the term for clinical deficiency of vitamin C (ascorbic acid). Although encountered less often today than in the past, it still occurs and mild cases may go unrecognized.

 

Patients at risk for vitamin C deficiency:

(1) infants

(2) adults > 55 years of age, especially males

(3) refugees or displaced persons

(4) malnutrition

(5) heavy cigarette smokers

(6) abnormal diets devoid of vegetables and vitamins

 

Clinical features of scurvy - bleeding tendency:

(1) petechiae

(2) purpura

(3) ecchymoses

(4) subperiosteal hemorrhage

(5) bleeding gums

(6) intracranial hemorrhage, which may be fatal

(7) conjunctival hemorrhages

 

Clinical features of scurvy - oral:

(1) gingival swelling and gingivitis

(2) loose or missing teeth

(3) scurvy buds on the gingiva

 

Clinical features of scurvy - skeletal changes in children:

(1) bowing of long bones in the lower extremities

(2) scorbutic rosary (depression of sternum with projection of the ends of the ribs)

(3) tender or aching limbs

 

Clinical features of scurvy - other:

(1) anemia

(2) hyperkeratosis

(3) abnormal wound healing

(4) poor localization of bacterial infections

(5) fatigue or weakness

 

The diagnosis of scurvy involves both of the following:

(1) the presence of clinical features in a person with a risk factor for vitamin C deficiency

(2) low blood levels of vitamin C, or clinical response to ascorbic acid replacement

 

  References:

Cotran RS, Kumar V, et al (editors). Robbins Pathologic Basis of Disease, 5th Edition. WB Saunders Company. 1994. pages 423-425.

Sauberlich HE. Laboratory Tests for the Assessment of Nutritional Status, Second Edition. CRC Press. 1999. pages 12-13.

 

 

   Excel Sheet | Reference TOP
     Pubmed Search For
Copy and paste the article title, or authors names into the search box