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Overview :
Seicean et al identified risk factors for mortality in
patients with chronic pancreatitis. These can help identify a patient who may
benefit from more aggressive management or a novel therapy. The authors are
from the University of Medicine and Pharmacy in Cluj-Napoca, Romania.
Risk factors associated with mortality in multivariate
analysis:
(1) continuation of smoking (not stopping)
(2) diabetes mellitus
(3) failure of pain control despite appropriate therapy
where:
• The relative
risks in Table 1, page 24, range from 1.25 to 1.58, which are not very large.
Additional findings associated with mortality:
(1) weight loss (falling body mass index)
Significnat causes of death included:
(1) pancreatic cancer
(2) extra-pancreatic cancer (lung, head and neck, other)
(3) massive upper gastrointestinal bleeding
(4) complications of surgery
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